women's health
Menopause has long been accepted as a fact of life for women, but what if there was a way to prevent hot flashes, night sweats, mood changes, and other unpleasant side effects?
Researchers in New York believe they have found the answer.
Scientists at biotechnology company Oviva Therapeutics have determined that levels of reproductive hormones such as estrogen, progesterone, and anti-Mullerian hormone can potentially and indefinitely influence the onset of menopause, which occurs between the ages of 45 and 55. announced that they have developed an injection that may delay the outbreak. Hormone (AMH) decreases.
“This drug can not only delay menopause, it can actually prevent it,” Dr. Daisy Robinton, a molecular biologist at Obiva Therapeutics, told the Daily Mail.
The jab increases levels of AMH, which is produced in the ovaries and is involved in ovulation, and may then halt menopause prematurely.
“The AMH hormone controls the lag to menopause, and in women it actually acts as a brake,” she explained while presenting her findings at the Livelong Summit in Florida, according to the Daily Mail.
“AMH may help slow the decline in ovarian reserve.” [number of eggs in the ovaries] and extend the runway to menopause. ”
The breakthrough drug, administered every few months, has been tested for safety in rodents and, if proven successful, could be tested in humans within a few years.
If approved for human use in the future, the treatment could cost six figures due to high research costs, according to the Daily Mail.
Although the researchers did not emphasize any adverse effects associated with the injections, hormone replacement therapy (which increases estrogen and progesterone levels in menopausal women and reduces symptoms, but does not delay the onset of symptoms) may It has been linked to an increased risk of blood clots and blood clots. And a stroke.
In an interview with Pharmacy Times earlier this month, Robinton said: “Our ovaries and women's bodies are in many ways a source of health, and the hormones they produce provide a type of homeostasis and consistent quality of life during a woman's reproductive years. “If her reproductive organs are functioning within normal limits.''
This is not just about long-term fertility. “When women reach menopause, their risk of cardiovascular disease increases significantly and their neurocognitive health declines significantly (so many women experienced 'brain fog'). Increased anxiety, depression, and mood disorders; [and] It's a serious sleep disorder. ”
This study builds on recent calls for a different approach to menopause.
Another team of experts, published in The Lancet this month, said menopause should not be considered a condition to be treated, but rather a natural consequence of aging.
“Symptom management is important, but the medical view of menopause leaves women feeling powerless and leads to overtreatment, which leads to improved mental health and freedom from menstruation, menstrual disorders, and contraception as we age. Potential positive effects may be missed,” they said. I have written.
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